How is “what are you on” used?

In Go (1999), one line is: “Professional curiosity. What are you on?”

Which movie is “what are you on” from?

The clip at the top of this page is from Go (1999).

Professional curiosity. What are you on?

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イディオム

used when you are very surprised at sb's behaviour and are suggesting that they are acting in a similar way to sb using drugs

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what are you, etc. on?
used when you are very surprised at sb's behaviour and are suggesting that they are acting in a similar way to sb using drugs

定義：Oxford Advanced Learner's Dictionary 第 9 版