What does “are you out of your mind” mean?

A rhetorical question showing shock or disapproval that someone's plan, action, or remark is crazy or reckless.

How is “are you out of your mind” used?

In Tucker and Dale vs. Evil (2010), one line is: “Are you out of your mind, Tucker? These are college girls.”

The clip at the top of this page is from Tucker and Dale vs. Evil (2010).

Are you out of your mind, Tucker? These are college girls.

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