筋疲力尽;智穷力竭;山穷水尽
牛津电影里 100%
to feel that you cannot deal with a difficult situation any more because you are too tired, worried, etc.
He is out of control, and I am at the end of my rope.
I'm at the end of my rope.
释义来自《牛津高阶英汉双解词典》第 9 版