What does “the die is cast” mean?

used to say that an event has happened or a decision has been made that cannot be changed

How is “the die is cast” used?

In Tombstone (1993), one line is: “No sir, the die is cast. We are growin'.”

The clip at the top of this page is from Tombstone (1993).

No sir, the die is cast. We are growin'.

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