How is “look up” used?

In Mysterious Skin (2005), one line is: “Now, um, look up into the camera.”

Which movie is “look up” from?

The clip at the top of this page is from Mysterious Skin (2005).

to raise your eyes when you are looking down at sth; to look for information in a dictionary or reference book, or by using a computer

informal · Heard in 110 movies

Oxford70% of films
to raise your eyes when you are looking down at sth
Oxford15% of films
to look for information in a dictionary or reference book, or by using a computer

Definitions from the Oxford Advanced Learner's Dictionary, 9th edition

Now, um, look up into the camera.

Said in 8 films · #1